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The weekend sees the initial Wear-Tyne derby since 2024, but who will emerge victorious – the Black Cats or the Magpies?
"For most of last season, it was unthinkable the Wearside club getting promoted and challenging with Eddie Howe's Newcastle, never mind being above them in the table," commented pundit Chris Sutton.
"It is very different now, and the way Sunderland play makes me think they've got a solid shot."
Sutton is making predictions for all 380 Premier League games this season, in competition with artificial intelligence, readers and a range of guests.
For this weekend's fixtures, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the England's esports team – the Football Association's formal esports team – at the EA Sports FC digital Euros finals tournament, which is being held at Twickenham Stadium on Saturday.
The action will be streamed on Uefa's YouTube, IG Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and the national team's Twitch.
What are your thoughts with their scores? You can make your own predictions below.
The fan-favourite scoreline chosen for each game is displayed on the leaderboards at the bottom of this page.
A correct result (choosing a win, draw or defeat) is worth 10 points. An accurate scoreline earns 40 points.
Ray, who also plays his club side and Manchester City as well as England, is competing for the first time at the eEuros finals after passing the qualification rounds.
A group of eight will fly the flag at the finals in a knockout format, vying for a substantial cash prize and a coveted spot in the global championship qualifiers, with the Danish representative Anders Vejrgang defending the title he won last year.
"I am feeling really good for it," Ray said. "I have a really good coach with me and practice has been going well.
"It is invariably an honour to play for your country. Naturally when you are younger, you fantasise about doing it as an professional footballer, but when you enter this job and there is an opportunity to represent England, wearing the Three Lions is something unique.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"In my opinion he is the top competitor in the world so getting a win over him in a tournament like this just gives you a massive injection of confidence."
Premier League Predictions
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were excellent against Arsenal at the end of November, when they earned a stalemate after being reduced to 10 men, and I was thinking they've turned a corner, they could possibly be challengers for the crown.
However, since that game, however, they were beaten physically by Leeds, looked flat against Bournemouth and this week got turned over by Atalanta in the Champions League.
So boss Enzo Maresca is in need of a win here to get back on track, but it will be a challenge because the Merseyside club are such a dangerous team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing exceptionally and Everton have got a bit of a positive run at the moment.
Current evidence suggests you would likely back the visitors, while the most prudent prediction would probably be a draw, but I'm going against logic.
The Blues have failed to given me any compelling evidence to back them recently, but I just have a feeling Chelsea will take this one because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be interesting to see what we get from Liverpool.
I am really pleased for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot should not have to put up with that drama. I know Salah has been a icon for the club but at its core Slot just wants to win games and there is nothing personal in his team selection.
Liverpool changed their shape against Inter and went with a midfield diamond formation and two up top.
The media is going to be talking about whether Salah is back for this game, but the only way he is going to be brought back into the fold is if he says sorry.
Slot's focus will be on winning this game, but it is a challenging encounter.
One might suggest it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are defensively susceptible too.
Liverpool need to get back to winning consistently, but I am not sure how much their exertions at the San Siro will have taken out of them.
I've selected a couple of Brighton players in my FPL team, so they will almost certainly blank - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Wearside club have had the opportunity to rest while Newcastle had to work so hard against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Apart from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been poor, particularly straight after they've played in the Champions League.
It is anticipated that that trend to continue on Sunday, and their tiredness is likely to be a significant issue in how this game goes because of their rivals' intensity.
We saw how incessant Regis le Bris's side are. They overpowered the Gunners, and it was incredible to watch.
Commentators talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been superb, but Noah Sadiki, who plays next to him, has also been one of the best acquisitions and warrants praise too.
All signs point to this being the best game|most exciting fixture